Journal: Clinical Mass Spectrometry
Article Title: A simplified, rapid LC-MS/MS assay for serum and salivary creatinine
doi: 10.1016/j.clinms.2018.11.004
Figure Lengend Snippet: Effect of bilirubin on measured creatinine. Five serum samples were spiked with bilirubin in DMSO or with DMSO alone, and the bilirubin concentration and icteric index were measured on an Abbott Architect analyser. Abbott Jaffe creatinine and LC-MS/MS creatinine values are plotted against icteric index (A, C) or measured bilirubin (B, D).
Article Snippet: The percentage change in measured creatinine compared to the unspiked sample was calculated for both creatinine methods. (B) Fifteen patient samples with high concentrations of endogenous glucose were analysed for creatinine by both assays and the % difference between the Abbott Jaffe method and the LC-MS/MS assay is shown for each sample.
Techniques: Concentration Assay, Liquid Chromatography with Mass Spectroscopy